Tyrosinase Inhibition: General and Applied Aspects
نویسندگان
چکیده
منابع مشابه
Inhibition of the Tyrosinase Oxidation
The catalytic oxidation of catechol by crude preparations of mushroom tyrosinase was studied by a method yielding data on initial reaction velocities. Graphical analysis of the results suggests that an excess of catechol inhibits its own oxidation by a competitive process, thus accounting for the observed optimum in the substrate concentration. However, added phenol, though itself a substrate, ...
متن کاملFermented broth in tyrosinase- and melanogenesis inhibition.
Fermented broth has a long history of applications in the food, pharmaceutical and cosmetic industries. Recently, the use of fermented broth in skin care products is in ascendance. This review investigates the efficacy of fermented broth in inhibiting tyrosinase and melanogenesis. Possible active ingredients and hypopigmentation mechanisms of fermented broth are discussed, and potential applica...
متن کاملThe inhibition effects of melon on mushroom tyrosinase activity
The inhibition effects seed and peel of melon on diphenolase activity of mashroom tyrosinase were investigated. The IC50 values and Ki values of seed and peel of melon were evaluated. increased the Km value and decreased the Vm value so it show mixed type inhibition on mushroom tyrosinase when L-DOPA was used as a substrate.
متن کاملKinetic cooperativity of tyrosinase. A general mechanism.
Tyrosinase shows kinetic cooperativity in its action on o-diphenols, but not when it acts on monophenols, confirming that the slow step is the hydroxylation of monophenols to o-diphenols. This model can be generalised to a wide range of substrates; for example, type S(A) substrates, which give rise to a stable product as the o-quinone evolves by means of a first or pseudo first order reaction (...
متن کاملCatalysis – Applied and Physical Aspects
Large amounts of CO adsorption resulted from a pulse adsorption experiment at 323 K,giving ~300% Pt dispersion in the title catalyst.An in situ DRIFTS investigation showed that carbonate species on the Ce oxide surface are responsible for the CO adsorption, as a result of CO spillover. Lowering the temperature to 195 K reduced the amount of CO adsorption.The Pt particle size could be determined...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Enzyme Inhibition and Medicinal Chemistry
سال: 2002
ISSN: 1475-6366,1475-6374
DOI: 10.1080/14756360210000010923